Stars like Zach Braff leave due to burnout, departing Scrubs to take a break from TV.

Burnout causes exit

Seeking opportunitie

Some actors exit to pursue opportunities, like Jennifer Raine leaving Call the Midwife for US roles.

Killed off on show

To explain absences, characters are killed off like Rayna Jaymes on Nashville.

Recast role

Main roles often recast, like Ashton Kutcher replacing Charlie Sheen on Two and a Half Men.

Format change

Shows change format when leads depart, as The X-Files did without Mulder.

Ratings suffer

Continuing without a main star can hurt ratings, like The Office minus Steve Carell.

Guest appearance

Main stars sometimes return as guests, like Carell’s finale cameo on The Office.

Creative difference

Actors leaving over creative disputes, like Connie Britton’s Nashville departure.

Seeking better role

Some stars exit over dissatisfaction with roles, like Farrah Fawcett on Charlie's Angels.

Scandals prompt exit

Scandals lead to firings like Kevin Spacey from House of Card